At Imago, our research is focused on therapeutics that can change the behavior of malignant blood cells through targeting lysine-specific demethylase 1 (LSD1): an enzyme that controls how genes are turned ‘on’ and ‘off’ in specific cells. LSD1 plays an essential role in the step-wise maturation of cells in the bone marrow. LSD1 plays a unique role in each step of blood cell formation and function.